Currently many researches have revealed that the activation of AURKA has a crucial role in multiple cancers, for example, gastric cancer (48), liposarcoma (49), neuroblastoma (50), pancreatic cancer (51), gastrointestinal cancer (52), hepatocellular carcinoma (53), leukemia (54), epithelial ovarian cancer (55), head and neck squamous cell carcinoma (56), prostate cancer (57), bladder cancer (58), upper gastrointestinal adenocarcinoma (59), fertile tumor of the bone marrow (60), oral squamous cell carcinoma (61), KIF20A was highly expressed. Here, KIF20A is linked to head and neck squamous cell carcinoma.