ALK and lung adenocarcinoma: We assessed common hotspot mutation regions for copy number alterations in lung adenocarcinomas to determine their concurrences and associations with LOH in KRAS. The copy number changes and the LOH statistics for EGFR, TP53, ALK, ERBB2, BRAF, MET, RET, ROS1, HER2, NTRK, STK11, and PIK3CA are given in Table 4.