In 2018, we reported the construction of a competitive endogenous RNA (ceRNA) regulation network linking the protein-coding functional mRNA to the mechanistically related lncRNAs based on the integrated omics analysis, which has further confirmed that dysregulation of RUNX1 is a key pathological inducer of the mesenchymal GBM subtype (23). Here, RUNX1 is linked to glioblastoma.