Additionally, no other overt signs of distress (e.g. anaphylaxis, death) were observed in mice using up to 6x106 ADMC i.v. To assess the efficacy of ADMC as anti-tumor cells, luciferase-luciferase-expressing HER2/neu+ BT474-1261 cells were implanted in immunocompromised mice then injected intratumorally (i.t.)with dye-labelled HER2/neu IgE-sensitized ADMC cells and visualized using a whole-body scanner. Here, ERBB2 is linked to anaphylaxis.