Similarly, at day 4 MC-treated tumors had significant upregulation of inhibitors of angiogenesis [CNNM1 (35), FILIP1L (36)], tumor suppressors [VWA5A (37), SYNPO2 (38), ALDH1A2 (39)], and those found overexpressed in certain tumors with unknown function [MPV17 (40)] (Figures 6D–F). Here, SYNPO2 is linked to neoplasm.