Further research and bioinformatics prediction found that PELATON and P53 can form a complex through the RNA-binding protein EIF4A3, which suggests a possible mechanism by which PELATON mediates ferroptosis in p53 wild-type or mutant GBM cells (Figure 3H and Supplementary Tables 2, 3) (48). This evidence concerns the gene EIF4A3 and glioblastoma.