Because METTL3 plays a critical role in catalytic activity, many studies regarding its biological function in cancers have been widely reported, including lymphoma (29, 30), leukemia (31–33), breast cancer progression (34), liver cancer (35), glioblastoma (36, 37), bladder cancer (38, 39), gastric cancer (40), and lung cancer (41, 42). The gene discussed is METTL3; the disease is cancer.