In an effort to link lactate, as a positive modulator of cell proliferation and migration, to the underlying molecular mechanisms activated in GBM cell lines, we performed Western blot analysis for the lactate transporters MCT1 and MCT4 and for β-catenin and E-cadherin on the control and lactate-treated U-87 MG, A-172, and U-251 MG cells. Here, CDH1 is linked to glioblastoma.