In summary, we identified that 9 lncRNAs (SNHG11, STK24-AS1, AL590483.1, MIR210HG, DNMBP-AS1, AL928654.1, AC019330.1, FAM87A, and HAR1A) in the prognostic risk model could be used to predict survival rates, and that 2 mRNAs (HOXA10 and NHLRC3) are related to the prognosis of COAD. This evidence concerns the gene FAM87A and colon adenocarcinoma.