Similarly, GRP78 (glucose-regulated protein 78, HSPA5) modification through chloramine adduction (Lys 353) has been suggested to modulate autophagy and apoptosis in A549 lung cancer cells, and N-chlorination of HSA (human serum albumin) converts plasma proteins into efficient activators of the phagocytic respiratory burst (46, 86). The gene discussed is HSPA5; the disease is lung carcinoma.