For MMP-7, it was discovered that MMP-7 rs11568818 was markedly related to bladder cancer susceptibility among the overall populations under the allelic and recessive models (allelic model, OR = 1.204, 95% CI = 1.055–1.374, p = 0.006; recessive model, OR = 1.538, 95% CI = 1.198–1.974, p = 0.001) instead of the dominant model; however, in Asians, MMP-7 rs11568818 was obviously related to bladder cancer risk (allelic model, OR = 1.229, 95% CI = 1.056–1.431, p = 0.008; recessive model, OR = 1.560, 95% CI = 1.166–2.087, p = 0.003). This evidence concerns the gene MMP7 and urinary bladder carcinoma.