Finally, 12 associations (MMP-2 rs243865 with esophageal cancer risk and LC risk, MMP-7 rs11568818 with bladder risk and CC risk, and MMP-9 rs3918242 with BC risk) were rated as strong evidence, 7 as moderate evidence, and 15 as weak. This evidence concerns the gene MMP7 and laryngotracheoesophageal cleft.