At last, 12 associations (MMP-2 rs243865 with esophageal cancer and LC, MMP-7 rs11568818 with bladder and CC, and MMP-9 rs3918242 with BC) were rated as strong evidence for cancer risk, 7 as moderate evidence, and 15 as weak. Here, MMP7 is linked to laryngotracheoesophageal cleft.