MMP2 and esophageal cancer: To be specific, in our research, a significant association between MMP-2 rs243865 and esophageal cancer risk in Asians was demonstrated (allelic model, OR = 0.751, 95% CI = 0.643–0.877, p < 0.001; dominant model, OR = 0.723, 95% CI = 0.607–0.862, p < 0.001).