COMMD2 was expressed at significantly higher levels in the tumor tissues of 10 various cancer types, including bladder cancer (BLCA), cervical squamous cell carcinoma (CESC), cholangiocarcinoma (CHOL), colorectal adenocarcinoma (COAD), esophageal cancer (ESCA), glioblastoma multiforme (GBM), head and neck squamous cell carcinoma (HNSC), LIHC, lung squamous cell carcinoma (LUSC) and stomach adenocarcinoma (STAD), than in the corresponding normal tissues. This evidence concerns the gene COMMD2 and head and neck squamous cell carcinoma.