52 PRGs were extracted from mRNA expression data from TCGA CESC cohort through literature mining, of which 19 genes were differentially expressed in normal and tumor samples, 11 genes were related to the prognosis of CESC patients (Table 2), and three genes (CHMP4C, GZMB, TNF) intersected together were prognostic DEPRGs (Figure 2A). Here, GZMB is linked to neoplasm.