DLG4 and Mental deterioration: Our previous studies indicated that the exposure of CD-1 female mice to LPS induces inflammation during late pregnancy, accelerates age-associated cognitive decline and exacerbates age-related changes in the levels of synaptic plasticity-related proteins (including Syntaxin-1, Syt1, Arc, PSD-95, GluA1, and Homer-1b/c) in both the mother and their offspring [13–16].