IGF1R and central nervous system cancer: WT 5 (U87WT 5) and Mut 5 (U87Mut 5) cells had comparable levels of IGF1R mRNA expression than those observed in samples from high-grade gliomas from pediatric patients (Figure 1A, P GB) that we used as a reference for expression levels, while U87WT50 and U87Mut 50 expressed much higher mRNA levels of IGF1R.