As shown in Table 2, the univariate logistic regression analysis showed the male sex, age, ICU LOS, ventilation, CHF, HBP, CKD, ARDS, SBP, DBP, MAP, Hb, RBC, platelet, HbA1c, Scr, lactic acid, SOFA score, SAPSII, OASIS, TRF, TIBC, SF, and TRF saturation were risk factors for AKI in critically ill patients with diabetes (P < 0.05). The gene discussed is GSTM1; the disease is chronic kidney disease.