Furthermore, in common with many screening HTAs, we assumed 100% screening adherence.Currently, uptake within the national bowel cancer screening program isapproximately 40%.25 Similarly, the FIT cutoff of 45 μg Hb/g as used in the program would generatefewer false positives than we inferred by using a 40-μg Hb/g cutoff. Here, GSTM1 is linked to intestinal cancer.