TCIRG1 and severe congenital neutropenia: Our findings shed light on TCIRG1 nsSNPs, their conservation, impact on protein stability and functions, protein 3D structure, PTM potential sites, ligand binding sites, and gene-gene interactions with other genes, all of which could be useful in future TCIRG1 research to better understand its role in diseases such as osteopetrosis and congenital neutropenia.