In ESCA (Figure 5B), KIRC (Figure 5C), LUSC (Figure 5D), and SARC (Figure 5G), CASP3 methylation levels were high, whereas in BLCA (Figure 5A), PRAD (Figure 5E), KIRP (Figure 5F), testicular germ cell tumours (TGCT; Figure 5H), and UCEC (Figure 5I), the reverse was true. The gene discussed is CASP3; the disease is childhood testicular germ cell tumor.