CASP3 and pancreatic adenocarcinoma: In STAD (p < 0.001), UCEC (p < 0.001), BRCA (p < 0.001), ACC (p = 0.002), COAD (p = 0.002), LGG (p = 0.002), PRAD (p = 0.015), and pancreatic adenocarcinoma (PAAD, p = 0.025), CASP3 expression was positively correlated with TMB, whereas was negatively correlated in UVM (p = 0.003), THCA (p < 0.001), and LIHC (p = 0.044, Figure 7A).