Vimentin intermediate filaments are well-recognized auto-antigens in sarcoidosis (Kinloch et al., 2018) and are shown to cause clonal expansion of lung-specific Vα2.3 + Vβ22 + CD4 + T lymphocytes in the granuloma (Kinloch et al., 2018). The gene discussed is VIM; the disease is sarcoidosis.