SOX4 and cancer: While both are linked to neurogenesis and neuronal crest cell formation (Bergsland et al., 2006; Martini et al., 2013; Uy et al., 2015), increased SOX4 expression is also commonly linked with several forms of cancer, in particular lung cancer, and has been suggested as a driver oncogene (Liu et al., 2006; Castillo et al., 2012).