HAGLR and cholangiocarcinoma: LncRNA HOTTIP and HOXD-AS1 were reported to regulate the sensitivity of CCA cells to gemcitabine and cisplatin through sponging miR-637 to increase LASP1 and sponging miR-520c-3p to increase MYCN, respectively (Figures 2C,D) (Li et al., 2020b; Gao et al., 2021).