CCAT2 and cholangiocarcinoma: Xu et al. (2018a) and Bai et al. (2018) both documented that the level of CCAT2 expression was inversely linked with the overall survival rate of CCA patients. The study suggested that CCAT2 has practicalvaluein predicting the prognosis of patients with ICC, with an AUC of 0.702 and 0.715 for OS and PFS, respectively (Bai et al., 2018). Besides, a meta-analysis in 2019 showed that upregulated CCAT lncRNA families, especially CCAT2, can predict shorter overall survival (p < 0.001) (Dai et al., 2019).