However, cross-disease comparisons between AD, frontotemporal lobe dementia (FTLD) and dementia with Lewy bodies (DLB) reveal that CSF GFAP concentrations are significantly increased in all three diseases compared to controls, with FTLD concentrations being significantly greater compared to AD and DLB (Ishiki et al., 2016). The gene discussed is GFAP; the disease is Lewy body dementia.