The Cox proportional risk model analysis illustrated (Figure 4A) CBX3 as a high-risk gene in adrenal cortical carcinoma (ACC), BRCA, HNSC, renal chromophobe cell carcinoma (KICH), low-grade glioma (LGG), LIHC, PAAD, and SARC. Here, CBX3 is linked to low grade glioma.