A recent observational study has reported findings of secondary TMA-mediated acute kidney injury (AKI) among COVID-19 patients, particularly when accompanied by a low ADAMTS13 (a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13) to vWF:Ag (von Willebrand factor antigen) ratio (15). Here, RENBP is linked to acute kidney injury.