However, cerebellar atrophy can also be found in some subtypes of HSPs such as SPG5A (22), SPG7 (20, 23), SPG11 (23, 24), SPG15 (25), SPG20 (26), SPG30 (27), SPG39 (28), and SPG46 (29). Here, PNPLA6 is linked to Cerebellar atrophy.