Conclusively, Yiqi Huayu Pinggan Zishen recipe combined with valsartan in the treatment of hypertension can remarkably relieve the clinical symptoms, strengthen renal function, enhance the therapeutic effect, facilitate the ability of independent movement, and reduce the levels of serum MMP-9, MCP-1, and Ang II and has high safety, so it has the value of clinical application. This evidence concerns the gene CCL2 and Hypertension.