Methyl rosmarinate (degree, 8; betweenness centrality, 0.02733; closeness centrality, 0.4715) also shared the same targets (STAT3, PIK3CB, MAPK1, ESR1, SYK, and EGFR) and identical asthma-related signaling pathways with caffeic acid. This evidence concerns the gene ESR1 and asthma.