HLA-A and leukemia: When we co-cultured NT or TCR8+ VSTs with HLA-A*02:01+survivin+ BV173 leukemia cells, we observed significant killing of target cells by TCR8+ but not NT VSTs (residual tumor cell count NT vs TCR8+: 2.3±0.6x106 vs 0.04±0.07x106, p=0.0004, mean±SD, n=6) (Figure 4A, left).