HLA-A and leukemia: As expected, TCR8+ but not NT VSTs produced IFN-γ in response to the cognate survivin peptide (LML) or the HLA-A*02:01+survivin+ leukemia cell line BV173, targeted by the transgenic TCR (IFN-γ SFCs NT vs TCR8+ VSTs; LML: 7.0±3.7 vs 577±268, p=0.003; BV173: 71.5±122 vs 925±246 p<0.0001, n=6, mean±SD) (Figure 3A, top left).