In HCMV-reactivating individuals, on days 90 and 180, the proportion of KIR2DL2/L3 single-positive/NKG2C+ NK cells among NKG2C+ NK cells was consistently higher than that of KIR2DL1 and KIR3DL1 NK cells (data not shown), which suggested that HCMV infection might not affect the expansion of KIR2DL2/L3 single-positive/NKG2C+ NK cells. The gene discussed is KLRC2; the disease is cytomegalovirus infection.