CXCL2 and neoplasm: In agreement with the above study, Axl KO cells secreted lower amounts of CCL2, CSF1, CXCL1, and CXCL2, but also altered the secretome of other cell types such as tumor-associated CD206-macrophages, which were shown to produce less VEGFA, CXCL1, and CXCL2.