In cecal ligation and puncture (CLP)-induced sepsis model in T-cell-specific autophagy related protein 7 (Atg7)-knockout mice and control mice, the mice with T-cell autophagy deficiency had higher mortality via suppressing bacterial clearance in the spleen, they finally proposed that autophagy might inhibit sepsis-induced apoptosis and immunosuppression in T lymphocytes (122). The gene discussed is ATG7; the disease is Sepsis.