Our previous studies have demonstrated that GCMSC-derived IL-8 induces PD-L1 expression in GC cells via the STAT3/mTOR-c-Myc signaling axis and that blocking IL-8 and IL-15 derived from GCMSCs overcomes the immune escape induced by PD-L1 in GC cells (8). The gene discussed is IL15; the disease is gastric cancer.