A variety of miRNAs, including miR-21, miR-26, miR-221/222, miR-210, miR-155, and miR-10b, promote GBM cell proliferation, apoptosis, and growth by targeting PTEN expression and active Akt and HIF3α. Recently, a growing number of studies revealed the relationship between miRNAs and inflammation (100, 105, 131–133). This evidence concerns the gene PTEN and glioblastoma.