Similarly, another study comparing melatonin and oxytocin in the prevention of critical illness polyneuropathy rats with experimentally induced sepsis showed that individually melatonin and oxytocin or co-administration of melatonin with oxytocin abolishes the nerve electrophysiologic alterations, increases muscle strength and suppresses oxidative stress, lipid peroxidation, and TNF-α release in muscles caused by sepsis (223). This evidence concerns the gene TNF and Sepsis.