Oxytocin has been shown to reduce sepsis-induced lipid peroxidation as evidenced by decreased malondialdehyde (MDA) levels, serum CRP levels and renal structural damage (46, 219, 220) Table (1) The increase in serum levels of TNF-α, a key pro-inflammatory cytokine, in sepsis, is also significantly ameliorated by oxytocin treatment (220). This evidence concerns the gene TNF and Sepsis.