Among non-malignant conditions, are systemic sclerosis, Newcastle disease, Sjögren’s syndrome, traumatic brain injury, lupus nephritis, systemic lupus erythematosus, diabetes mellitus, and myocardial ischemia/reperfusion injury have been found to be associated with dysregulation of IFN-related non-coding RNAs. This evidence concerns the gene IFNA1 and Sjogren syndrome.