Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses of the 47 differentially expressed genes enriched in the T-defect group indicated enrichment in several T cell-related immunodeficiency pathways and JAK/STAT, NF-κB, and HIF-1 signaling pathways (Figures 4A, B). Here, NFKB1 is linked to immune system disorder.