ADAMTS14 and nonpapillary renal cell carcinoma: To further evaluate the diagnostic power of ADAMTS14, we conducted a ROC analysis and the 1-year, 3-year, and 5-year area under the curve (AUC) values were 0.728, 0.653, and 0.685, respectively, indicating a moderate diagnostic effect in diagnosing ccRCC based on the expression of ADAMTS14 (Figure 1G).