CYP2E1 and Parkinson disease: In addition, rs2070676 (CYP2E1) showed an association with PD in a Swedish population (Shahabi et al., 2009), rs1048943 (CYP1A1) was associated with PD in a Japanese population (Takakubo et al., 1996), and rs762551 (CYP1A2) was reported to have a marginal association with PD risk in the United States and Denmark (Palacios et al., 2010; Chuang et al., 2016).