A previous publication by our group using the same cohort but few participants showed Aβ42 and tau levels at 3 months were lower in the patients with PSCI at 1 year than in those without PSCI, which may reveal AD pathology one mechanism of PSCI development after 3 months of stroke and decreased levels of plasma tau could be explained by its association with the decreased plasma Aβ42 levels (Chi et al., 2019). Here, MAPT is linked to stroke disorder.