↓β-catenin expression in G2 and G4 ↓ NFκB-p65, COX-2 and TNFα inflammatory proteins ↑ pro-apoptotic proteins Bax casp3 and p53 ↓ VEGFα expression in G4 ↓ tumor incidence in G2. This evidence concerns the gene NFKB1 and neoplasm.