TPO and thyroid gland disorder: Se supplementation did not affect maternal thyroid peroxidase antibody (TPO Ab) or thyroglobulin antibody (Tg Ab) from 12 to 35 weeks of gestation [49, 50] but resulted in a decrease of these antibody titres from 36 weeks' gestation to 6 months' postpartum in a thyroiditis positive population [48].