JAK2 and chronic obstructive pulmonary disease: Some scholars have established a rat model of COPD and found that the percentage of pulmonary artery fiber, serum IL-6 content, and the expression of p-JAK2 and p-STAT3 are decreased after the intervention of Baofei Dingchuan Decoction, indicating that it can significantly reduce the weight of pulmonary blood vessels and improve lung functions of COPD rats [17].