Other enriched pathways include TGF-Beta signaling pathway, ubiquitin-mediated proteolysis, FoxO signaling pathway, non-small-cell lung cancer, melanoma, endometrial cancer, central carbon metabolism in cancer, and chronic myeloid leukemia which are also considered to be closely related to the occurrence and development of tumors. This evidence concerns the gene TGFB1 and chronic myelogenous leukemia, BCR-ABL1 positive.