JAK1 and gastric cancer: According to one recent work, ARMCX1, which directly targets miR-106 in gastric cancer, is upregulated and can rescue the cell apoptosis and promoted the phosphorylation level of JAK-STAT by miR-106b inhibitor, while interestingly, decreased miR-106b expression promotes GC cell apoptosis by suppressing JAK1/STAT3 pathway in vivo and in vitro [22].