GLRA2 defects were indeed reported in individuals with autism spectrum disorder (ASD; Pinto et al., 2010; Piton et al., 2011; Iossifov et al., 2014; Pilorge et al., 2016), although additional clinical symptoms were reported in some cases, including delay/loss of acquired language and seizures (Piton et al., 2011; Pilorge et al., 2016). This evidence concerns the gene GLRA2 and autism spectrum disorder.