PRDX1, PRDX2, and PRDX3 expressions downregulated in papillary and anaplastic thyroid cancers, PRDX4 mRNA expression was moderately increased in anaplastic thyroid cancer tissues, and PRDX6 expression status showed similar levels as well as normal thyroid and thyroid cancers [128]. This evidence concerns the gene PRDX4 and thyroid gland undifferentiated (anaplastic) carcinoma.