IGF2BP2 and type 2 diabetes mellitus: In addition, Zhang et al. (59) showed that IGF2BP2 increased smooth muscle 22 alpha (SM22α) mRNA stability by serving as the “reader” of m6A-modified SM22α, which further inhibited the proliferation and migration of VSMCs and alleviated intimal hyperplasia in T2DM, revealing the protective role of IGF2BP2 in VSMCs dysfunction.