In our study, 10 FRGs (STEAP3, HSPB1, MAP1LC3A, SOCS1, LOX, CAPG, CP, GDF15, CDKN1A, and CD44) associated with IDH1 status in GBM were identified, and survival analysis suggested that all these genes were of significant risk. The gene discussed is LOX; the disease is glioblastoma.