A meta-analysis constituting 21 RCTs involving 1,566 patients revealed that oral Chinese herbal medicine effectively improves overall efficacy, LVEF, LVEDD, stroke volume (SV), BNP, and 6MWD in the treatment of DCM (Zhu et al., 2016), which was consistent with our results. Here, NPPB is linked to familial dilated cardiomyopathy.