IL1A and COVID-19: In addition, we found that the anti-COVID-19 and anti-STAD effects of VD3 may be associated with core genes such as IL1A, CXCL8, ALB, CSF2, and SERPINE1. Next, we speculated that the anti-COVID-19/STAD effects of VD3 might be associated with the core genes IL1A, CXCL8, ALB, CSF2 and SERPINE1, and then did molecular docking to verify the speculation.